Jun 202013
 

ABM-TKI 0.11

:: DESCRIPTION

ABM-TKI is a tool, employing agent-based model (ABM), to simulate brain tumor growth that includes an EGFR signaling pathway together with a related cell-cycle pathway, angiogenesis and tyrosine kinase inhibitors (TKIs) treatment. The users can apply this tool to predict the responses of brain cancer to TKIs, and to reveal the dual role of angiogenesis during TKI treatment.

::DEVELOPER

Center for Bioinformatics & Systems Biology

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / MacOsX / Linux
  • Matlab

:: DOWNLOAD

  ABM-TKI

:: MORE INFORMATION

Citation

Multi-scale agent-based brain cancer modeling and prediction of TKI treatment response: incorporating EGFR signaling pathway and angiogenesis.
Sun X, Zhang L, Tan H, Bao J, Strouthos C, Zhou X.
BMC Bioinformatics. 2012 Aug 30;13:218. doi: 10.1186/1471-2105-13-218.

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