3FunMap is a Windows software that can be used to construct genetic linkage maps and perform functional QTL mapping with molecular markers generated in a full-sib family. For linkage analysis, the software utilizes seven segregation types of markers to estimate the recombination and simultaneously predict the linkage phase between any two markers. It takes heuristic search method for ordering large number of markers of a linkage group by incorporating local ordering methods. Multi-locus linkage phases for the optimal order of each linkage group are predicted based on three-point linkage analysis.
Center for Statistical Genetics, Penn State University
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Bioinformatics. 2011 Jul 15;27(14):2006-8. doi: 10.1093/bioinformatics/btr306. Epub 2011 May 17.
3FunMap: full-sib family functional mapping of dynamic traits.
Tong C, Wang Z, Zhang B, Shi J, Wu R.