3DGarden (Global and Restrained Docking Exploration Nexus) is an integrated software suite for performing protein-protein and protein-polynucleotide docking. For any pair of biomolecules structures specified by the user, 3DGarden’s primary function is to generate an ensemble of putative complexed structures and rank them. The highest-ranking candidates constitute predictions for the structure of the complex. 3DGarden cannot be used to decide whether or not a particular pair of biomolecules interacts. Complexes of protein and nucleic acid chains can also be specified as individual interactors for docking purposes.
Structural Bioinformatics Group, Imperial College
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3D-Garden: a system for modelling protein-protein complexes based on conformational refinement of ensembles generated with the marching cubes algorithm.
Lesk VI, Sternberg MJ.
Bioinformatics. 2008 May 1;24(9):1137-44. doi: 10.1093/bioinformatics/btn093.